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The Rheumatology Research Unit

Department of Rheumatology
Odense University Hospital OUH - Southern University of Denmark


Research area:
Aspects of early diagnosis, treatment, disease activity, pathogenesis, prognosis, biomarkers, comorbidity, compliance, adherence and quality of life in: 

  • Rheumatoid arthritis
  • Psoriatic arthritis
  • Spondyloarthropathy
  • Arthritis urica
  • Sarcoidosis
  • ANCA-associated vasculitis
  • Systemic lupus erythematosus
  • Cerebral vasculitis
  • Systemic sclerosis
  • Idiopathic inflammatory myopathies
  • Tendinopathy


In clinically well characterised cohorts/trials:
Inception and trans-sectional cohorts
Investigator initiated trials

Randomized and open treatment strategy studies with synthetic and biological DMARD (Disease Modifying Anti Rheumtic Drugs) as well as training strategies.


Using:
Immunological and molecular-biological techniques:

Including ELISA, flow-cytometry, immunohistochemistry (synovium, tendons, muscles, arteria temporalis, kidneys), western-blotting, SNP-genetics, micro-RNA, proteomics), cellular immunology (in vitro migration, mononuclear and stem cell proliferation-assays), pharmacokinetics.

Imaging:  
PET-CT, CT, MRI and, ultrasound of joints, tendons (including elastography) as well as the heart (SPECKLE TRECK, MRI-perfusion stress test and CT-KAG) and carotis.

Epidemiological and interview based approaches, structured meta-analysis:
Survival models, treatment outcome and prognosis.

 


Siden er sidst opdateret: 12-02-2018 af Odense Universitetshospital.