Aspects of early diagnosis, treatment, disease activity, pathogenesis, prognosis, biomarkers, comorbidity, compliance, adherence and quality of life in:
In clinically well characterised cohorts/trials:
Inception and trans-sectional cohorts
Investigator initiated trials
Randomized and open treatment strategy studies with synthetic and biological DMARD (Disease Modifying Anti Rheumtic Drugs) as well as training strategies.
Immunological and molecular-biological techniques:
Including ELISA, flow-cytometry, immunohistochemistry (synovium, tendons, muscles, arteria temporalis, kidneys), western-blotting, SNP-genetics, micro-RNA, proteomics), cellular immunology (in vitro migration, mononuclear and stem cell proliferation-assays), pharmacokinetics.
PET-CT, CT, MRI and, ultrasound of joints, tendons (including elastography) as well as the heart (SPECKLE TRECK, MRI-perfusion stress test and CT-KAG) and carotis.
Epidemiological and interview based approaches, structured meta-analysis:
Survival models, treatment outcome and prognosis.
Siden er sidst opdateret: 12-02-2018 af Odense Universitetshospital.