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OUHs arteriebiobank - videnskabelige arbejder


Eksempler på videnskabelige artikler, hvor arteriemateriale fra Odense indgår: 

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.
Hansen PB, Poulsen CB, Walter S, Marcussen N, Cribbs LL, Skøtt O, Jensen BL.
Hypertension. 2011 Sep;58(3):464-70. doi: 10.1161/HYPERTENSIONAHA.111.170845.
Epub 2011 Jul 25.


Fibulin-1 is a Marker for Arterial Extracellular Matrix Alterations in Type 2 Diabetes.
Cangemi, C, Skov V, Poulsen, MK, Funder, J, Twal WO, Gall, MA, Hjortdal, V, Jespersen, ML, Kruse, TA, Aagard, J, Parving, HH, Knudsen, S, Høilund-Carlsen, PF, Rossing, P, Henriksen, JE, Argraves, WS, Rasmussen, LM
Clin Chem, 57, 1556-1565, 2011


Global gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes.
Skov, V, Knudsen, S, Olesen, M, Hansen, ML, Rasmussen, LM
Cardiovasc Diabetol, in press 2012, Cardiovasc Diabetol. 2012 Feb
17;11:15. doi: 10.1186/1475-2840-11-15. PubMed PMID: 22340758; PubMed Central PMCID: PMC3348024.


Niacin and biosynthesis of PGD2 by platelet COX-1 in mice and humans
Song, WL, Stubbe, J, Ricciotti, E, Alamuddin, N, Ibrahim, S, Critchon, I, Prempeh, M, Lawson, JA  Wilensky, R, Rasmussen, LM, Pure, E, FitzGerald, GA
J Clin Invest, in press 2012, J Clin Invest. 2012 Apr
2;122(4):1459-68. doi: 10.1172/JCI59262. Epub 2012 Mar 12. PubMed PMID: 22406532; PubMed Central PMCID: PMC3314457.
 

Angiotensin II Regulates microRNA-132/-212 in Hypertensive Rats and Humans.
Jeppesen, PL, Eskildsen, T, Bjørling-Poulsen, M,  Skov, VH, Schneider, M, Andersen, DC, Bie, P, Rasmussen, LM, Sheikh, SPInt J Mol Sci. 2013 May 27;14(6):11190-207. doi: 10.3390/ijms140611190.
 


Igangværende projekter, som benytter materiale fra arteriebiobanken:

  • Insulin signalling in the arterial wall in diabetes (prof LM Rasmussen)
     
  • Dual effect of prostaglandins on human artery contractility (prof BL Jensen)
     
  • Elastin metabolism in the vasculature in type 2 diabetes. (prof LM Rasmussen)
     
  • T-type Calcium channels in the development of hypertension (ass. prof. PL Hansen)
     
  • Associations between arterial stiffness, biochemical markers and glycemic status in diabetes (LMR)
     
  • Insulin resistance in the arterial wall among patients ith type 2 diabetes. (LMR)

 


Siden er sidst opdateret: 30-10-2013 af Odense Universitetshospital.